Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3
The neurodegenerative disease spinocerebellar ataxia type 3 (SCA3) is caused by a CAG-repeat expansion in the ATXN3 gene. In this study, induced pluripotent stem cell (iPSC) lines were established from two SCA3 patients. Dermal fibroblasts were reprogrammed using an integration-free method and the r...
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| Glavni autori: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2016-09-01
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| Serija: | Stem Cell Research |
| Online pristup: | http://www.sciencedirect.com/science/article/pii/S1873506116300769 |
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