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Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3

The neurodegenerative disease spinocerebellar ataxia type 3 (SCA3) is caused by a CAG-repeat expansion in the ATXN3 gene. In this study, induced pluripotent stem cell (iPSC) lines were established from two SCA3 patients. Dermal fibroblasts were reprogrammed using an integration-free method and the r...

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Bibliografski detalji
Glavni autori: Susanne K. Hansen, Tina C. Stummann, Helena Borland, Lis F. Hasholt, Zeynep Tümer, Jørgen E. Nielsen, Mikkel A. Rasmussen, Troels T. Nielsen, Justus C.A. Daechsel, Karina Fog, Poul Hyttel
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016-09-01
Serija:Stem Cell Research
Online pristup:http://www.sciencedirect.com/science/article/pii/S1873506116300769
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