White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition

Abstract Multi-compartment modelling of white matter microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI) can provide information on white matter health through neurite density index and free water measures. We hypothesized that cerebrovascular disease, Alzheimer’s disease...

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Detalhes bibliográficos

Principais autores:	Sheelakumari Raghavan, Scott A. Przybelski, Robert I. Reid, Timothy G. Lesnick, Vijay K. Ramanan, Hugo Botha, Billie J. Matchett, Melissa E. Murray, R. Ross Reichard, David S. Knopman, Jonathan Graff-Radford, David T. Jones, Val J. Lowe, Michelle M. Mielke, Mary M. Machulda, Ronald C. Petersen, Kejal Kantarci, Jennifer L. Whitwell, Keith A. Josephs, Clifford R. Jack, Prashanthi Vemuri
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-02-01
coleção:	Acta Neuropathologica Communications
Assuntos:	Diffusion tensor imaging Neurite dispersion density imaging Cerebrovascular disease Tau positron emission tomography TAR DNA binding protein of 43 kDa
Acesso em linha:	https://doi.org/10.1186/s40478-022-01319-6
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