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Coordination between ESCRT function and Rab conversion during endosome maturation

Abstract The endosomal pathway is essential for regulating cell signaling and cellular homeostasis. Rab5 positive early endosomes receive proteins from the plasma membrane. Dependent on a ubiquitin mark on the protein, they will be either recycled or sorted into intraluminal vesicles (ILVs) by endos...

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Bibliographic Details
Main Authors: Daniel P Ott, Samit Desai, Jachen A Solinger, Andres Kaech, Anne Spang
Format: Artigo
Language:Inglês
Published: Springer Nature 2025-02-01
Series:The EMBO Journal
Subjects:
Online Access:https://doi.org/10.1038/s44318-025-00367-7
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