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CAR-modified Cellular Therapies in Chronic Lymphocytic Leukemia: Is the Uphill Road Getting Less Steep?

The clinical development of chimeric antigen receptor (CAR) T-cell therapy has been more challenging for chronic lymphocytic leukemia (CLL) compared to other settings. One of the main reasons is the CLL-associated state of immune dysfunction that specifically involves patient-derived T cells. Here,...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Candida Vitale, Valentina Griggio, Francesca Perutelli, Marta Coscia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2023-12-01
Schriftenreihe:HemaSphere
Online-Zugang:http://journals.lww.com/10.1097/HS9.0000000000000988
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