An RNAi Screen Reveals an Essential Role for HIPK4 in Human Skin Epithelial Differentiation from iPSCs

Molecular mechanisms responsible for the development of human skin epithelial cells are incompletely understood. As a consequence, the efficiency to establish a pure skin epithelial cell population from human induced pluripotent stem cells (hiPSCs) remains poor. Using an approach including RNAi and...

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Detalhes bibliográficos

Principais autores:	Lionel Larribère, Marta Galach, Daniel Novak, Karla Arévalo, Hans Christian Volz, Hans-Jürgen Stark, Petra Boukamp, Michael Boutros, Jochen Utikal
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2017-10-01
coleção:	Stem Cell Reports
Assuntos:	keratinocytes iPSC HIPK4 differentiation RNAi screen epithelium skin stem cell organotypic culture development
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213671117303806
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