Longitudinal changes in frailty, insulin resistance and incident cardiovascular-kidney- metabolic syndrome progression in middle-aged and older adults: evidence from CHARLS

Abstract Background Although frailty has been associated with individual components of cardiovascular-kidney-metabolic (CKM) syndrome, the overall relationship between frailty and CKM syndrome, as well as the potential mediating role of insulin resistance (IR), remains inadequately understood. Metho...

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Detalhes bibliográficos

Principais autores:	Qi Huang, Xian Luo, Tao Yang, XiaoMan Qing, XinMei Zhang, MingZhu Xiu, Zheng Liu, Hao Li, Sha Liu, Wanmeng Xiao, Muhan Lü, Song Su
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
Colecção:	Diabetology & Metabolic Syndrome
Assuntos:	Frailty Insulin resistance Cardiovascular-kidney-metabolic syndrome CHARLS
Acesso em linha:	https://doi.org/10.1186/s13098-025-02030-x
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