The eEF2 kinase coordinates the DNA damage response to cisplatin by supporting p53 activation

Abstract Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) is a stress-responsive hub that inhibits the translation elongation factor eEF2, and consequently mRNA translation elongation, in response to hypoxia and nutrient deprivation. EEF2K is also involved in the response to DNA damage but its r...

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Autori principali:	Jonathan K. M. Lim, Arash Samiei, Alberto Delaidelli, Jessica Oliveira de Santis, Vanessa Brinkmann, Christopher J. Carnie, Daniel Radiloff, Laura Hruby, Alisa Kahler, Jordan Cran, Gabriel Leprivier, Poul H. Sorensen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2024-07-01
Serie:	Cell Death and Disease
Accesso online:	https://doi.org/10.1038/s41419-024-06891-4
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