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Radiotherapy enhances responses of lung cancer to CTLA-4 blockade

Abstract Formenti et al. have recently reported the clinical outcomes and translational readouts of a trial of the anti-CTLA-4 inhibitor, ipilimumab, in combination with palliative radiotherapy in 39 patients with non-small cell lung cancer. A radiological response was seen in 18% of patients and 31...

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Autori principali: Anna Wilkins, Fiona McDonald, Kevin Harrington, Alan Melcher
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2019-03-01
Serie:Journal for ImmunoTherapy of Cancer
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Accesso online:http://link.springer.com/article/10.1186/s40425-019-0542-z
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