Enhancers and silencers: an integrated and simple model for their function

<p>Abstract</p> <p>Regulatory DNA elements such as enhancers, silencers and insulators are embedded in metazoan genomes, and they control gene expression during development. Although they fulfil different roles, they share specific properties. Herein we discuss some examples and a parsimonious model...

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Bibliografiske detaljer

Principais autores:	Kolovos Petros, Knoch Tobias A, Grosveld Frank G, Cook Peter R, Papantonis Argyris
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2012-01-01
Serier:	Epigenetics & Chromatin
Fag:	enhancer silencer insulator transcription factory hub long-range interactions chromosome conformation capture three-dimensional genome architecture
Online adgang:	http://www.epigeneticsandchromatin.com/content/5/1/1
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