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Protective Effects of Alpha-Lipoic Acid on Methotrexate-Induced Oxidative Lung Injury in Rats

Objective: Oxidative stress is one of the major causes of methotrexate induced lung injury (MILI). Alpha-lipoic acid (ALA), which occurs naturally in human food, has antioxidative and anti-inflammatory activities. The aim of this study was to research the potential protective role of ALA on MILI in...

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Hlavní autoři: Huseyin Arpag, Mehmet Gül, Yusuf Aydemir, Nurhan Atilla, Birgül Yiğitcan, Tugrul Cakir, Cemal Polat, Özer Þehirli, Muhammet Sayan
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2018-03-01
Edice:Journal of Investigative Surgery
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On-line přístup:http://dx.doi.org/10.1080/08941939.2017.1296513
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