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Development of CAR Exosomes Targeting FAP for the Treatment of Intrauterine Adhesion

ABSTRACT Engineered extracellular vesicles (EVs) have emerged as promising cell‐free platforms for immunomodulation and tissue repair. In this study, we generated EVs derived from chimeric antigen receptor (CAR) T cells targeting fibroblast activation protein (FAP) and investigated their biological...

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Principais autores: Wenyan Fu, Kewen Qian, Hongru Ai, Yitan Zou, Yaping Zhou, Ruixue Mao, Jian Zhao, Changhai Lei, Shi Hu
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2026-05-01
coleção:Journal of Extracellular Vesicles
Assuntos:
immunotherapy
CAR‐T
exosomes
FAP
intrauterine adhesions
Acesso em linha:https://doi.org/10.1002/jev2.70284
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