Biologically relevant laminin as chemically defined and fully human platform for human epidermal keratinocyte culture

In vitro expansion of human epidermal keratinocytes to resurface severe wound defects still relies on a human/mouse xenograft culture system. Here the authors develop a fully human, xeno-free culture system using skin-associated laminins, normally present in vivo, to replace mouse feeder cells.

Detalhes bibliográficos

Principais autores:	Monica Suryana Tjin, Alvin Wen Choong Chua, Aida Moreno-Moral, Li Yen Chong, Po Yin Tang, Nathan Peter Harmston, Zuhua Cai, Enrico Petretto, Bien Keem Tan, Karl Tryggvason
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2018-10-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-018-06934-3
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