Factor H interferes with the adhesion of sickle red cells to vascular endothelium: a novel disease-modulating molecule

Sickle cell disease is an autosomal recessive genetic red cell disorder with a worldwide distribution. Growing evidence suggests a possible involvement of complement activation in the severity of clinical complications of sickle cell disease. In this study we found activation of the alternative comp...

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Главные авторы:	Elisabetta Lombardi, Alessandro Matte, Antonio M. Risitano, Daniel Ricklin, John D. Lambris, Denise De Zanet, Sakari T. Jokiranta, Nicola Martinelli, Cinzia Scambi, Gianluca Salvagno, Zeno Bisoffi, Chiara Colato, Angela Siciliano, Oscar Bortolami, Mario Mazzuccato, Francesco Zorzi, Luigi De Marco, Lucia De Franceschi
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Ferrata Storti Foundation 2019-05-01
Серии:	Haematologica
Online-ссылка:	https://haematologica.org/article/view/8894
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