Combined Use of Astragalus Polysaccharide and Berberine Attenuates Insulin Resistance in IR-HepG2 Cells via Regulation of the Gluconeogenesis Signaling Pathway

Insulin resistance (IR) is likely to induce metabolic syndrome and type 2 diabetes mellitus (T2DM). Gluconeogenesis (GNG) is a complex metabolic process that may result in glucose generation from certain non-carbohydrate substrates. Chinese herbal medicine astragalus polysaccharides and berberine ha...

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Autori principali:	Zhu-Jun Mao, Min Lin, Xin Zhang, Lu-Ping Qin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2019-12-01
Serie:	Frontiers in Pharmacology
Soggetti:	astragalus polysaccharide berberine insulin resistance IR-HepG2 cell model intracellular calcium flux gluconeogenesis signaling pathway
Accesso online:	https://www.frontiersin.org/article/10.3389/fphar.2019.01508/full
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