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The reaction mechanism of the Ideonella sakaiensis PETase enzyme

Abstract Polyethylene terephthalate (PET), the most abundantly produced polyester plastic, can be depolymerized by the Ideonella sakaiensis PETase enzyme. Based on multiple PETase crystal structures, the reaction has been proposed to proceed via a two-step serine hydrolase mechanism mediated by a se...

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Autori principali: Tucker Burgin, Benjamin C. Pollard, Brandon C. Knott, Heather B. Mayes, Michael F. Crowley, John E. McGeehan, Gregg T. Beckham, H. Lee Woodcock
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-03-01
Serie:Communications Chemistry
Accesso online:https://doi.org/10.1038/s42004-024-01154-x
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