High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic Strategies

High Mobility Group Box 1 (HMGB1) is a highly conserved non-histone chromatin-associated protein across species, primarily recognized for its regulatory impact on vital cellular processes, like autophagy, cell survival, and apoptosis. HMGB1 exhibits dual functionality based on its localization: both...

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Hauptverfasser: Sayantap Datta, Mohammad Atiqur Rahman, Saisudha Koka, Krishna M. Boini
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-11-01
Schriftenreihe:Cells
Schlagworte:
HMGB1
cardiovascular diseases
renal dysfunction
receptor for advanced glycation end products (RAGE)
Online Zugang:https://www.mdpi.com/2073-4409/13/23/1946
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