LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells
Canonical Wnt/β-catenin signaling is frequently dysregulated in myeloid leukemias and is implicated in leukemogenesis. Nuclear-localized β-catenin is indicative of active Wnt signaling and is frequently observed in acute myeloid leukemia (AML) patients; however, some patients exhibit little or no nu...
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| Principais autores: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2019-07-01
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| Colecção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/8967 |
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