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Insights into mitotic checkpoint by integrating CRISPR and RNAi

Our recent study of the mitotic checkpoint protein BUB1 (budding uninhibited by benzimidazoles 1) revealed several apparent BUB1 knock-out cell lines expressing low levels of BUB1 protein sufficient to support spindle assembly checkpoint activity. This rings alarm bells on the application of CRISPR...

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Bibliografske podrobnosti
Glavni avtor: Gang Zhang
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis Group 2019-07-01
Serija:Molecular & Cellular Oncology
Teme:
Online dostop:http://dx.doi.org/10.1080/23723556.2019.1603436
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