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A DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast.

Specialized chromatin exists at centromeres and must be precisely transmitted during DNA replication. The mechanisms involved in the propagation of these structures remain elusive. Fission yeast centromeres are composed of two chromatin domains: the central CENP-A(Cnp1) kinetochore domain and flanki...

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Библиографические подробности
Главные авторы: Toyoaki Natsume, Yasuhiro Tsutsui, Takashi Sutani, Elaine M Dunleavy, Alison L Pidoux, Hiroshi Iwasaki, Katsuhiko Shirahige, Robin C Allshire, Fumiaki Yamao
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2008-05-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC2376062?pdf=render
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