Role of CDK4 as prognostic biomarker in Soft Tissue Sarcoma and synergistic effect of its inhibition in dedifferentiated liposarcoma sequential treatment

Abstract Soft tissue sarcomas represent an heterogeneous group of rare mesenchymal tumors comprising 1% of all solid malignancies. Among them, liposarcoma is one of the most common histotypes with atypical lipomatous tumor/well differentiated liposarcoma and dedifferentiated liposarcoma (ALT/WDLPS a...

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Hauptverfasser:	Silvia Vanni, Giacomo Miserocchi, Graziana Gallo, Valentina Fausti, Sofia Gabellone, Chiara Liverani, Chiara Spadazzi, Claudia Cocchi, Chiara Calabrese, Giovanni De Luca, Massimo Bassi, Manlio Gessaroli, Nicola Tomasetti, Angelo Campobassi, Federica Pieri, Giorgio Ercolani, Davide Cavaliere, Lorena Gurrieri, Nada Riva, Federica Recine, Toni Ibrahim, Laura Mercatali, Robin Jones, Alessandro De Vita
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-08-01
Schriftenreihe:	Experimental Hematology & Oncology
Online-Zugang:	https://doi.org/10.1186/s40164-024-00540-4
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