Lithocholic acid attenuates DON-induced inflammatory responses via epigenetic regulation of DUSP5 and TRAF5 in porcine intestinal epithelial cells

Deoxynivalenol (DON) is the most common mycotoxin that frequently contaminates human food and animal feed, resulting in intestinal diseases and systemic immunosuppression. Lithocholic acid (LCA) exhibits various pharmacological activities. RNA-seq and ChIP-qPCR analysis were used in the current stud...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Shiqi Wang, Xiaoxu Peng, Qi Zhu, Sichen Lu, Ping Hu, In Ho Kim, Hao-Yu Liu, Wael Ennab, Madesh Muniyappan, Demin Cai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-02-01
Colecção:	Frontiers in Veterinary Science
Assuntos:	epigenetics histone modification porcine deoxynivalenol lithocholic acid
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fvets.2025.1493496/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!