p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock

Sepsis is a major cause of morbidity and mortality in seriously ill patients and mitochondrial dysfunction is associated with poor outcomes in septic patients. Although interleukin-6 (IL-6) is a good prognostic marker for sepsis, the relationship between mitochondrial dysfunction and IL-6 remains po...

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Autors principals:	Katsuhiko Sasaki, Kazuhito Gotoh, Sho Miake, Daiki Setoyama, Mikako Yagi, Ko Igami, Takeshi Uchiumi, Donchon Kang
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2017-06-01
Col·lecció:	EBioMedicine
Matèries:	LPS Il-6 Mitochondria ATF4 p32
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2352396417302165
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