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Impaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome

Fragile X syndrome (FXS) is the most common monogenetic cause of inherited intellectual disability and autism in humans. One of the well-characterized molecular phenotypes of Fmr1 KO mice, a model of FXS, is increased translation of synaptic proteins. Although this upregulation stabilizes in adultho...

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Principais autores: Magdalena Chojnacka, Anna Beroun, Marta Magnowska, Aleksandra Stawikowska, Dominik Cysewski, Jacek Milek, Magdalena Dziembowska, Bozena Kuzniewska
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-11-01
coleção:Frontiers in Molecular Neuroscience
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1258615/full
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