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DNA Methylation Signature in Monozygotic Twins Discordant for Psoriatic Disease

Background: Psoriatic disease is a multifactorial inflammatory condition spanning from skin and nail psoriasis (Pso) to spine and joint involvement characterizing psoriatic arthritis (PsA). Monozygotic twins provide a model to investigate genetic, early life environmental exposure and stochastic inf...

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Principais autores: Matteo Vecellio, Elvezia Maria Paraboschi, Angela Ceribelli, Natasa Isailovic, Francesca Motta, Giulia Cardamone, Michela Robusto, Rosanna Asselta, Sonia Brescianini, Francesco Sacrini, Antonio Costanzo, Maria De Santis, Maria Antonietta Stazi, Stefano Duga, Carlo Selmi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-11-01
coleção:Frontiers in Cell and Developmental Biology
Assuntos:
DNA methylation
twins
psoriartic arthritis
psoriatic disease
transcriptomic (RNA-seq)
epigenetics (DNA methylation)
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2021.778677/full
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