Separating the effects of life course adiposity on diabetic nephropathy: a comprehensive multivariable Mendelian randomization study

AimsPrevious Mendelian randomization (MR) of obesity and diabetic nephropathy (DN) risk used small sample sizes or focused on a single adiposity metric. We explored the independent causal connection between obesity-related factors and DN risk using the most extensive GWAS summary data available, con...

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Hauptverfasser:	Han Zhang, QingYa Zhang, YiJue Song, LiJun Wang, MinChao Cai, JinFang Bao, Qing Yu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-02-01
Schriftenreihe:	Frontiers in Endocrinology
Schlagworte:	Mendelian randomization diabetic nephropathy life course adiposity childhood obesity obesity
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1285872/full
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