Genetic Features of a Representative Panel of 110 Meningococcal B Isolates to Assess the Efficacy of Meningococcal B Vaccines

ABSTRACT Predictions of vaccine efficacy against Neisseria meningitidis serogroup B (NmB) disease are hindered by antigenic variability, limiting the representativeness of individual NmB isolates. A qualitative human serum bactericidal assay using endogenous complements of individual subjects (enc-h...

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Detalhes bibliográficos

Principais autores:	Alessandro Muzzi, Margherita Bodini, Nadav Topaz, Vega Masignani, Kumaran Vadivelu, Henju Marjuki, Xin Wang, Laura Serino, Duccio Medini
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2022-10-01
coleção:	mSphere
Assuntos:	meningococcal disease 4CMenB MenB-FHbp vaccine effectiveness serogroup B bacterial isolates
Acesso em linha:	https://journals.asm.org/doi/10.1128/msphere.00385-22
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