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Combining viral genomics and clinical data to assess risk factors for severe COVID-19 (mortality, ICU admission, or intubation) amongst hospital patients in a large acute UK NHS hospital Trust.

Throughout the COVID-19 pandemic, valuable datasets have been collected on the effects of the virus SARS-CoV-2. In this study, we combined whole genome sequencing data with clinical data (including clinical outcomes, demographics, comorbidity, treatment information) for 929 patient cases seen at a l...

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Principais autores: Max Foxley-Marrable, Leon D'Cruz, Paul Meredith, Sharon Glaysher, Angela H Beckett, Salman Goudarzi, Christopher Fearn, Kate F Cook, Katie F Loveson, Hannah Dent, Hannah Paul, Scott Elliott, Sarah Wyllie, Allyson Lloyd, Kelly Bicknell, Sally Lumley, James McNicholas, David Prytherch, COVID-19 Genomics UK (COG-UK) consortium, Andrew Lundgren, Or Graur, Anoop J Chauhan, Samuel C Robson
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2023-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0283447&type=printable
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