NUP98 oncofusions in myeloid malignancies: An update on molecular mechanisms and therapeutic opportunities
Abstract Acute myeloid leukemia (AML) is an aggressive hematological malignancy with a heterogeneous molecular landscape. In the pediatric context, the NUP98 gene is a frequent target of chromosomal rearrangements that are linked to poor prognosis and unfavorable treatment outcomes in different AML...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley
2024-09-01
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| Serier: | HemaSphere |
| Online adgang: | https://doi.org/10.1002/hem3.70013 |
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