THE RELATIVE CONTRIBUTIONS OF GERMLINE VARIATION, EPIMUTATION, AND SOMATIC MUTATION TO PAEDIATRIC LEUKAEMIA PREDISPOSITION
The next-generation sequencing era has repeatedly demonstrated that the amount of acquired somatic mutations in paediatric cancers can rarely account for the total incidence of any cancer subtype. In addition, many cancer-related mutations can be found in healthy individuals. These findings strongly...
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| Formato: | Artigo |
| Idioma: | Inglês |
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European Medical Journal
2016-07-01
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| Series: | European Medical Journal Hematology |
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| Acceso en liña: | https://www.emjreviews.com/hematology/article/the-relative-contributions-of-germline-variation-epimutation-and-somatic-mutation-to-paediatric-leukaemia-predisposition/ |
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