Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study

Introduction Uncontrolled asthma is associated with substantial morbidity. While fast-acting bronchodilators provide quick relief from asthma symptoms, their use as rescue fails to address the underlying inflammation. Combining a short-acting beta2-agonist, such as albuterol (salbutamol), with an in...

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Hlavní autoři:	Alberto Papi, Bradley E Chipps, Frank C Albers, Laurence Reilly, Eva Johnsson, Christy Cappelletti
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMJ Publishing Group 2021-11-01
Edice:	BMJ Open Respiratory Research
On-line přístup:	https://bmjopenrespres.bmj.com/content/8/1/e001077.full
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