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Mebendazole inhibits PELI3-mediated ubiquitination of TRADD in non-small cell lung cancer cells

IntroductionTumor necrosis factor receptor 1-associated death domain protein (TRADD) can trigger proapoptotic autophagy in non-small cell lung cancer (NSCLC). While the potential ubiquitin-protein ligase (E3) against TRADD is not well deciphered.MethodsUbiBrowser was used to predict the potential E3...

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Furkejuvvon:
Váldodahkkit: Fannian Li, Xiaoning Li, Haitao Li, Shuai Li, Yanchao Liu, Xianhua Bai, Tianjie Qi, Xiumin Zhao, Yuzheng He
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2026-01-01
Ráidu:Frontiers in Oncology
Fáttát:
mebendazole
PELI3
TRADD
E3 ubiquitin ligase
non-small cell lung cancer
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fonc.2025.1728170/full
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