The genomic landscape of ANCA-associated vasculitis: Distinct transcriptional signatures, molecular endotypes and comparison with systemic lupus erythematosus

IntroductionAnti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) present with a complex phenotype and are associated with high mortality and multi-organ involvement. We sought to define the transcriptional landscape and molecular endotypes of AAVs and compare it to systemic lup...

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Detalhes bibliográficos

Principais autores:	Aggelos Banos, Konstantinos Thomas, Panagiotis Garantziotis, Anastasia Filia, Nikolaos Malissovas, Antigone Pieta, Dimitrios Nikolakis, Alexandros G. Panagiotopoulos, Aglaia Chalkia, Dimitrios Petras, George Bertsias, Dimitrios T. Boumpas, Dimitrios Vassilopoulos
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-03-01
coleção:	Frontiers in Immunology
Assuntos:	autoimmune diseases vasculitis lupus (SLE) transcriptomics (RNA-seq) endotypes of disease
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1072598/full
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