Case report: Curative effect and mechanism of surufatinib combined with toripalimab in the treatment of 1 case of lung large-cell neuroendocrine carcinoma

BackgroundLarge-cell neuroendocrine lung carcinoma (LCNEC) is a rare heterogeneous tumour with rates ranging from 2.1% to 3.5%. The overall prognosis of pulmonary LCNEC is poor, and the 5-year overall survival rate is only 21%. Advanced LCNEC treatment drugs are limited, and their efficacy is low. H...

Cur síos iomlán

Sonraí bibleagrafaíochta

Príomhchruthaitheoirí:	Shuanglong Xiong, Chengxiang Yang, Kaiwen Fu, Xingyun Liao, Yao Ding, Kexue Zhou, Li Zhang, Yan Teng, Chunman Wu, Yongsheng Li, Houjie Liang, Yan Li
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2025-09-01
Sraith:	Frontiers in Oncology
Ábhair:	lung large-cell neuroendocrine carcinoma Surufatinib toripalimab immune microenvironment TMB
Rochtain ar líne:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1527719/full
Clibeanna:	Cuir clib leis Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!