Impact of spleen volume and volume change in non-Hodgkin lymphoma treated with chimeric antigen receptor t-cell therapy

Purpose: Chimeric antigen receptor T-cell (CART) therapy targeting CD19 is effective for relapsed/refractory (r/r) lymphoma. As part of the lymphatic system, the spleen might influence CART outcomes. We examined how spleen volume (SV) and its changes affect progression-free (PFS) and overall surviva...

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Detalhes bibliográficos

Principais autores:	Christina Quell, Wolfgang G. Kunz, Viktoria Blumenberg, Kai Rejeski, Veit L. Bücklein, Maria Ingenerf, Christian Schmidt, Gabriel T. Sheikh, Matthias Brendel, Jens Ricke, Michael von Bergwelt-Baildon, Marion Subklewe, Michael Winkelmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-01-01
coleção:	Cancer Treatment and Research Communications
Assuntos:	Spleen CAR T-cell therapy Non-Hodgkin-Lymphoma Immunotherapy
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2468294225002163
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