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Association between Hypothyroidism Onset and Alzheimer Disease Onset in Adults with Down Syndrome

Adults with Down syndrome (DS) have an exceptionally high frequency of Alzheimer disease (AD) with a wide variability in onset, from 40 to 70 years of age. Equally prevalent in DS is hypothyroidism. In this study, we sought to quantify the relationship between the two. A total of 232 adults with DS...

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Enregistré dans:
Auteurs principaux: Florence Lai, Nathaniel D. Mercaldo, Cassandra M. Wang, Micaela S. Hersch, Giovi G. Hersch, Herminia Diana Rosas
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2021-09-01
Collection:Brain Sciences
Sujets:
Down syndrome
early-onset Alzheimer disease
late-onset Alzheimer disease
hypothyroidism
thyroid autoantibodies
TSH
Accès en ligne:https://www.mdpi.com/2076-3425/11/9/1223
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