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del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts

We present the case of a patient with MDS RARS subtype with loss of part of the long arm of chromosome 11 del 11(q23). This a cytogenetic abnormality that occurs in 7% to 20% of RARS cases not related to poor prognosis. It seems that this deletion is a marker of iron overload in MDS.

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Hlavní autoři: Maria de Lourdes Lopes Ferrari Chauffaille, José Tadeu Stéfano, Rosana Maria Valério, Maura Romeo, Maria Madalena Rodrigues, José Kerbauy
Médium: Artigo
Jazyk:Inglês
Vydáno: Associação Paulista de Medicina
Edice:São Paulo Medical Journal
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On-line přístup:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000400010&lng=en&tlng=en
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