Naldemedine-induced perforation of a diverticulum in the sigmoid colon of a patient with opioid-related constipation: a case report

Abstract Background Naldemedine is an orally available peripherally acting μ-opioid receptor antagonist approved to treat opioid-induced constipation (OIC). It is contraindicated for patients with known or suspected gastrointestinal obstruction to protect against naldemedine-induced perforation. Her...

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Autori principali:	Hayato Yokota, Yumiko Akamine, Mizuki Kobayashi, Takuro Kitabayashi, Misato Horie, Tentaro Endo, Takechiyo Yamada, Masafumi Kikuchi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-08-01
Serie:	Journal of Pharmaceutical Health Care and Sciences
Soggetti:	Constipation Diverticulum Intestinal perforation Naldemedine Peripherally acting μ-opioid receptor antagonists
Accesso online:	https://doi.org/10.1186/s40780-024-00371-9
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