LSD1 is a targetable vulnerability in gastric cancer harboring TP53 frameshift mutations
Abstract Background TP53 mutations are linked to aggressive progression and chemoresistance in gastric cancer (GC). Frameshift mutation is the second most common mutation type of TP53. However, the consequences of this mutation type in GC were not well understood, and targeted therapies for cancer p...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2025-02-01
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| Serie: | Clinical Epigenetics |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s13148-025-01829-9 |
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