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Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study

Abstract Background Adaptations in lipid metabolism are essential to meet the physiological demands of pregnancy and any aberration may result in adverse outcomes for both mother and offspring. However, there is a lack of population-level studies to define the longitudinal changes of maternal circul...

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Hlavní autoři: Li Chen, Sartaj Ahmad Mir, Anne K. Bendt, Esther W. L. Chua, Kothandaraman Narasimhan, Karen Mei-Ling Tan, See Ling Loy, Kok Hian Tan, Lynette P. Shek, Jerry Chan, Fabian Yap, Michael J. Meaney, Shiao-Yng Chan, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Neerja Karnani, Markus R. Wenk
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2023-02-01
Edice:BMC Medicine
Témata:
Lipidomics
Preconception
Pregnancy
Postpartum
Weight changes
Metabolic adaptations
On-line přístup:https://doi.org/10.1186/s12916-023-02740-x
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