Several Human Cyclin-Dependent Kinase Inhibitors, Structurally Related to Roscovitine, As New Anti-Malarial Agents

In Africa, malaria kills one child each minute. It is also responsible for about one million deaths worldwide each year. Plasmodium falciparum, is the protozoan responsible for the most lethal form of the disease, with resistance developing against the available anti-malarial drugs. Among newly pro...

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主要な著者:	Sandrine Houzé, Nha-Thu Hoang, Olivier Lozach, Jacques Le Bras, Laurent Meijer, Hervé Galons, Luc Demange
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2014-09-01
シリーズ:	Molecules
主題:	Plasmodium falciparum cyclin-dependent kinases CDKs PfCDKs 2,6,9-trisubstituted purines roscovitine Buchwald-Hartwig amination
オンライン･アクセス:	http://www.mdpi.com/1420-3049/19/9/15237
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