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Differential cytokine regulation by NF-κB and AP-1 in Jurkat T-cells

<p>Abstract</p> <p>Background</p> <p>Activator protein (AP)-1 and nuclear factor (NF)-κB largely control T-cell activation, following binding of foreign antigens to the T-cell receptor leading to cytokine secretion. Elevated levels of pro-inflammatory cytokines and chemokines such as TNF, IL-6 and C...

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Bibliografische gegevens
Hoofdauteurs: Jass Jana, Khalaf Hazem, Olsson Per-Erik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2010-05-01
Reeks:BMC Immunology
Online toegang:http://www.biomedcentral.com/1471-2172/11/26
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