Locus coeruleus in the pathogenesis of Alzheimer's disease: A systematic review
Abstract The locus coeruleus (LC) is a nucleus in the brain stem producing noradrenaline. While cognitive decline in Alzheimer's disease (AD) has primarily been related to cholinergic depletion, evidence indicates extensive LC degeneration as its earliest pathological marker. The current study aimed...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2022-01-01
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| coleção: | Alzheimer’s & Dementia: Translational Research & Clinical Interventions |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1002/trc2.12257 |
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