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Synthetic lethality of PARP and NAMPT inhibition in triple‐negative breast cancer cells

Abstract PARP inhibitors have been proposed as a potential targeted therapy for patients with triple‐negative (ER‐, PR‐, HER2‐negative) breast cancers. However, it is as yet unclear as to whether single agent or combination therapy using PARP inhibitors would be most beneficial. To better understand...

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Bibliografische gegevens
Hoofdauteurs: Ilirjana Bajrami, Asha Kigozi, Antoinette Van Weverwijk, Rachel Brough, Jessica Frankum, Christopher J. Lord, Alan Ashworth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Nature 2012-08-01
Reeks:EMBO Molecular Medicine
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Online toegang:https://doi.org/10.1002/emmm.201201250
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