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In-depth LC-MS and in-vitro studies of a triterpenoid saponin capilliposide-A metabolism modulation in gut microbiota of mice

Introduction: Some herbal ingredients can reshape the composition of the gut microbiome as well as its metabolites. At the same time, the gut microbiota can also affect drug metabolism. A large number of studies have reported that saponins are biotransformed under the action of intestinal microorgan...

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Autori principali: Huan Zhao, Xueli Hu, Shenghong Guan, Jinhong Cai, Xiaohan Li, Jiaxi Fang, Bo Lin, Wei Zhu, Jingkui Tian, Juan Jin, Qiang He, Xiaoyong Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-03-01
Serie:Frontiers in Pharmacology
Soggetti:
gut microbiota
metabolite
triterpenoid
saponin
LC-MS
capilliposide A
Accesso online:https://www.frontiersin.org/articles/10.3389/fphar.2024.1361643/full
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