Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer’s Disease

Animal models of disease are valuable resources for investigating pathogenic mechanisms and potential therapeutic interventions. However, for complex disorders such as Alzheimer’s disease (AD), the generation and availability of innumerous distinct animal models present unique challenges to AD resea...

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Bibliografski detalji

Glavni autori:	Dominic I. Javonillo, Kristine M. Tran, Jimmy Phan, Edna Hingco, Enikö A. Kramár, Celia da Cunha, Stefania Forner, Shimako Kawauchi, Giedre Milinkeviciute, Angela Gomez-Arboledas, Jonathan Neumann, Crystal E. Banh, Michelle Huynh, Dina P. Matheos, Narges Rezaie, Joshua A. Alcantara, Ali Mortazavi, Marcelo A. Wood, Andrea J. Tenner, Grant R. MacGregor, Kim N. Green, Frank M. LaFerla
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-01-01
Serija:	Frontiers in Neuroscience
Teme:	Alzheimer’s disease amyloid β-protein tau neurofibrillary tangles amyloid precursor protein animal model
Online pristup:	https://www.frontiersin.org/articles/10.3389/fnins.2021.785276/full
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