Nanoscopic distribution of VAChT and VGLUT3 in striatal cholinergic varicosities suggests colocalization and segregation of the two transporters in synaptic vesicles

Striatal cholinergic interneurons (CINs) use acetylcholine (ACh) and glutamate (Glut) to regulate the striatal network since they express vesicular transporters for ACh (VAChT) and Glut (VGLUT3). However, whether ACh and Glut are released simultaneously and/or independently from cholinergic varicosi...

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Autors principals:	Paola Cristofari, Mazarine Desplanque, Odile Poirel, Alison Hébert, Sylvie Dumas, Etienne Herzog, Lydia Danglot, David Geny, Jean-François Gilles, Audrey Geeverding, Susanne Bolte, Alexis Canette, Michaël Trichet, Véronique Fabre, Stéphanie Daumas, Nicolas Pietrancosta, Salah El Mestikawy, Véronique Bernard
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-09-01
Col·lecció:	Frontiers in Molecular Neuroscience
Matèries:	striatum striatal cholinergic interneurons (CINs) vesicular acetylcholine transporter (VAChT) type 3 vesicular glutamate transporter (VGLUT3) STimulated Emission Depletion microscopy (STED) acetylcholine-glutamate cotransmission
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.991732/full
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