ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

Abstract Background Acute myeloid leukemia (AML) is an aggressive and mostly incurable hematological malignancy with frequent relapses after an initial response to standard chemotherapy. Therefore, novel therapies are urgently required to improve AML clinical outcomes. 4-Amino-2-trifluoromethyl-phen...

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Κύριοι συγγραφείς:	Yubin Feng, Xiaoxiao Hua, Ruowen Niu, Yan Du, Congjian Shi, Renpeng Zhou, Fei-Hu Chen
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2019-05-01
Σειρά:	Biological Research
Θέματα:	Acute myeloid leukemia Differentiation Proliferation ATPR ROS PTEN/PI3K/AKT
Διαθέσιμο Online:	http://link.springer.com/article/10.1186/s40659-019-0232-9
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