Profiling of RNA N6-Methyladenosine methylation reveals the critical role of m6A in betaine alleviating hepatic steatosis

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major predisposing factor of metabolic dysfunction-associated steatohepatitis, hepatic fibrosis and hepatocellular carcinoma. Abnormal RNA m6A modification leads to the disturbance of lipid metabolism, insulin resistance,...

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Autori principali:	Yuna Wu, Jingsu Yu, Haisen Song, Dehao Lu, Zhilin Li, Xiangling Li, Zhaoxuan Ding, Lei Zhou, Jie Ma, Ying Zhang, Yixing Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-03-01
Serie:	Scientific Reports
Soggetti:	Betaine MASLD N6-methyladenosine (m6A) MeRIP-seq Trub2
Accesso online:	https://doi.org/10.1038/s41598-025-91573-0
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