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Glycoside hydrolases enhance antibiotic activity against Pseudomonas aeruginosa biofilms from cystic fibrosis airways

ABSTRACT Pseudomonas aeruginosa forms antibiotic-tolerant biofilms in cystic fibrosis (CF) lungs. Targeting exopolysaccharides such as Psl and Pel offers a potential strategy to disrupt biofilms and improve antibiotic efficacy. Fourteen clinical CF P. aeruginosa isolates were screened for Psl- and P...

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Principais autores: Isaac Martin, Jonathan Chung, Deepa Raju, Yvonne Yau, Amanda J. Morris, Shafinaz Eisha, P. Lynne Howell, Valerie Waters
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2026-04-01
סדרה:Microbiology Spectrum
נושאים:
glycoside hydrolase
antibiotic adjuvant
biofilm
גישה מקוונת:https://journals.asm.org/doi/10.1128/spectrum.01354-25
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