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Activation of Proteinase-Activated Receptors Induces Itch-Associated Response Through Histamine-Dependent and -Independent Pathways in Mice

Proteinase-activated receptor-2 (PAR2) participates in itch, but the role of the other subtypes of this receptor remain unknown. To investigate this issue, scratching, an itch-related behavior, was observed following intradermal injections of the activating peptides of PAR1–4 in mice. Activating pep...

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Principais autores: Kenichiro Tsujii, Tsugunobu Andoh, Jung-Bum Lee, Yasushi Kuraishi
格式: Artigo
语言:Inglês
出版: Elsevier 2008-01-01
丛编:Journal of Pharmacological Sciences
在线阅读:http://www.sciencedirect.com/science/article/pii/S1347861319313477
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